Fresh frozen allograft in lumbar spine surgery. Does it increase the rate of infection?

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Published: Aug 19, 2018
DOI: https://doi.org/10.15417/issn.1852-7434.2018.83.3.753
Keywords:
Allograft, infection, vancomycin

Main Article Content

César Bartolomeo
Sanatorio Allende, Córdoba, Córdoba
Joint Halley Guimbard Pérez
Sanatorio Allende.
http://orcid.org/0000-0002-8887-8947
Pablo Nicolás Ortiz
Sanatorio Allende.
Mariano Pomba
Hospital Misericordia.
Gustavo Alejandro González
Sanatorio Allende.
David Orosco Falcone
Sanatorio Allende

Abstract

IntroductionPostoperative infection in lumbar spine is unfortunately common, multifactorial and a potentially devastating complication that is associated with increased morbidity and the need for future surgery, being eventually fatal. To reduce postoperative morbidity, medication and hospital stays, we began to use fresh-frozen bone allograft, femoral head from living donors in short lumbar arthrodesis. The aim of the present study was analyze the rate of infection in patients with short lumbar arthrodesis with fresh-frozen bone allograft versus bone autograft.MethodsRetrospective study in 153 patients divided into two groups: group A, 84 patients with iliac crest autograft and group B, 69 patients with fresh-frozen bone allograft, from March 2009 to January 2014, undergoing instrumented posterolateral lumbar spinal fusion surgery.ResultsThree of the 153 operated patients were lost at follow-up (2 in group A and 1 in group B) leaving the sample with 150 patients (82 in group A and 68 in group B). There were three infections caused by methicillin-sensitive Staphylococcus aureus in group A (4.5%). No patient required transfusion.ConclusionsThe use of fresh-frozen bone allograft in posterolateral lumbar spine surgeries for degenerative causes is not associated with an increase in the infection rate. We consider that fresh frozen bone allograft is an excellent alternative, because it reduces surgical and hospitalization times. 

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How to Cite
Bartolomeo, C., Guimbard Pérez, J. H., Ortiz, P. N., Pomba, M., González, G. A., & Orosco Falcone, D. (2018). Fresh frozen allograft in lumbar spine surgery. Does it increase the rate of infection?. Revista De La Asociación Argentina De Ortopedia Y Traumatología, 83(3), 188-191. https://doi.org/10.15417/issn.1852-7434.2018.83.3.753
Issue
Vol 83 No 3 (2018)
Section
Clinical Research
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Author Biographies

César Bartolomeo, Sanatorio Allende, Córdoba, Córdoba

Residente Ortopedia y Traumatología.

Joint Halley Guimbard Pérez, Sanatorio Allende.

Servicio de Patología Espinal.

Pablo Nicolás Ortiz, Sanatorio Allende.

Jefe departamento Patología Espinal.

Mariano Pomba, Hospital Misericordia.

Staff Médico.

Gustavo Alejandro González, Sanatorio Allende.

Staff Médico.

David Orosco Falcone, Sanatorio Allende

Spine Fellowship.

References

1. Khan SN, Cammisa FP Jr, Sandhu HS, Diwan AD, Girardi FP, Lane JM. The biology of bone grafting. J Am Acad Orthop Surg 2005;13:77-86.

2. Hanley EN Jr, David SM. Lumbar arthrodesis for the treatment of back pain. J Bone Joint Surg Am 1999;81:716-30.

3. Frymoyer JW, Nachemson A. Natural history of low back disorders. En: Frymoyer JW (ed). The adult spine: principles and practice, New York: Raven Press; 1991:1537-50.

4. Sasso RC, LeHuec JC, Shaffrey C, and the Spine Interbody Research Group. Iliac crest bone graft donor site pain after anterior lumbar interbody fusion. A prospective patient satisfaction outcome assessment. J Spinal Disord Tech 2005;18(Suppl):S77-81.

5. Buttermann GR, Glazer PA, Bradford DS. The use of bone allografts in the spine. Clin Orthop Relat Res 1996;(324):75-85.

6. Gruenberg N, Petracchi M, Valacco M, Solá C. Uso de vancomicina en injertos óseos como profilaxis de infección aguda en cirugía espinal. Coluna/Columna 2008;7(3)251-6.

7. Scheverin N, Steverlynck A, Castelli R, Sobrero D, Videla Kopp N, Dinelli D, et al. Prophylaxis of surgical site infection with vancomycin in 513 patients that underwent to lumbar fusion. Coluna/Columna 2015;14(3):177-80.

8. Fang A, Hu SS, Enders N, Bradford D. Risk factors for infection after spinal surgery. Spine 2005;30(12):1460-5.

9. Chahoud J, Kanafani Z, Kanj SS. Surgical site infections following spine surgery: eliminating the controversies in the diagnosis. Division of Infectious Diseases, Department of Internal Medicine, American University of Beirut Medical Center; 2014.

10. Allan DO, Levi MD, Dickman MD, Volker K. Management of postoperative infections after spinal instrumentation. J Neurosurg 1997;86:975-80.

11. Dimick JB, Lipsett PA, Kostuik JP. Spine update: antimicrobial prophylaxis in spine surgery. Spine 2000;25(19):2544-8.

12. Mikhael MM, Huddleston PM, Nassr A. Postoperative culture positive surgical site infections after de use of irradiated allograft, nonirradiated allograft, and autograft for spinal fusion. Spine (Phila Pa 1976) 2009;34(22):2466-8.