Mazabraud Syndrome: A Case Report

Main Article Content

Rodrigo Re
Maximiliano Negri
Jorge Flores

Abstract

Mazabraud’s Syndrome is a rare association of lesions to the musculoskeletal system. It results from the combination of one or more intramuscular myxomas and fibrous dysplasia. We present a case of a 46-year-old man with bone lesions compatible with fibrous dysplasia associated with intramuscular myxoma, configuring Mazabraud’s Syndrome, and a review of the literature.
 
 

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How to Cite
Re, R., Negri, M., & Flores, J. (2021). Mazabraud Syndrome: A Case Report. Revista De La Asociación Argentina De Ortopedia Y Traumatología, 86(3), 365-374. https://doi.org/10.15417/issn.1852-7434.2021.86.3.1102
Section
Case Presentations
Author Biographies

Rodrigo Re, Diagnostic Imaging Service, Osteoarticular / Musculoskeletal Area - Interventionism, Sanatorio Allende (Córdoba, Argentina)

Diagnostic Imaging Service, Osteoarticular / Musculoskeletal Area - Interventionism, Sanatorio Allende (Córdoba, Argentina)

Maximiliano Negri, Traumatology Service, Sanatorio Allende (Córdoba, Argentina)

Traumatology Service, Sanatorio Allende (Córdoba, Argentina)

Jorge Flores, Pathological Anatomy Service, Sanatorio Allende (Córdoba, Argentina)

Pathological Anatomy Service, Sanatorio Allende (Córdoba, Argentina)

References

1. Vescini F, Falchetti A, Tonelli V, Carpentieri M, Cipri C, Cosso R, et al. Mazabraud’s syndrome: a case report and
up-to-date literature review. Endocr Metab Immune Disord Drug Targets 2019;19(6):885-93.
https://doi.org/10.2174/1871530319666181226103700

2. Case DB, Chapman CN Jr, Freeman JK, Polga JP. Atypical presentation of polyostotic fibrous dysplasia with
myxoma (Mazabraud syndrome). RadioGraphics 2010;30:827-32. https://doi.org/10.1148/rg.303095155

3. Henschen F. Fall von ostitis Fibrosa mit multiplen Tumoren in derumgebenden Muskulatur. Verh Dtsch Ges Pathol
1926;21:93-7.

4. Mazabraud A, Girard J. [A peculiar case of fibrous dysplasia with osseous and tendinous localizations]. Rev Rhum Mal Osteoartic 1957;24(9-10):652-9. PMID: 13518962

5. Stout A. Myxoma: the tumor of primitive mesenchyme. Ann Surg 1948;127(4):706-19. PMID: 18917127

6. Nielsen GP, O’Connell JX, Rosenberg AE. Intramuscular myxoma: a clinicopathologic study of 51 cases with
emphasis on hypercellular and hypervascular variants. Am J Surg Pathol 1998;22(10):1222-7.
https://doi.org/10.1097/00000478-199810000-00007

7. Murphey MD, McRae GA, Fanburg-Smith JC, Levine AM, Aboulafia AJ. Imaging of soft-tissue myxoma with
emphasis on CT and MR and comparison of radiologic and pathologic findings. Radiology 2002;225(1):215-24.
https://doi.org/10.1148/radiol.2251011627

8. Nishio J, Naito M. FDG PET/CT and MR imaging of intramuscular myxoma in the gluteus maximus. World J Surg
Oncol 2012;10(1):132. https://doi.org/10.1186/1477-7819-10-132

9. Baltu Y, Arikan ŞM, Dölen UC, Uzun H, Alkan Bİ, Aydın O. Intramuscular myxoma: clinical and surgical
observation notes on eleven cases. Int Orthop 2017;41(4):837‐43. https://doi.org/10.1007/s00264-016-3396-8

10. Zoccali C, Teori G, Prencipe U, Erba F. Mazabraud’s syndrome: A new case and review of the literature. Int Orthop 2009;33(3):605-10. https://doi.org/10.1007/s00264-007-0483-x